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Princess Sophia of Sweden also Sofia Gustavsdotter Vasa (29 October 1547 – 17 March 1611), was a Swedish princess, daughter of King Gustav Vasa of Sweden and Margareta Leijonhufvud, a Swedish noble. She was formally Duchess consort of Saxe-Lauenburg as the spouse of duke Magnus II of Saxe-Lauenburg.
Princess Sofia is by many historians called the unhappiest of all the children of Gustav Vasa. She was married to Duke Magnus II of Saxe-Lauenburg, in a discreet ceremony in the shadow of her half-brother King Eric XIV's wedding to Karin Månsdotter on 4 July 1568. The marriage became extremely unhappy; the duke was an alcoholic known to mistreat his subordinates and his servants, and he abused her both mentally and physically in such a violent way that she became insane.